Are you craving a comforting, flavorful, and nutritious meal that’s quick to prepare but packs a punch in terms of taste? If you’re a fan of seafood, then a seafood casserole recipe might be just what you’re looking for. But what if I told you that this dish can be customized to suit various dietary preferences, and still deliver a rich and satisfying flavor? It’s true! Whether you’re cooking for family or hosting a dinner party, a seafood casserole can be a showstopper. But the real question is: how can you make it both delicious and healthy without compromising on taste? Let’s explore the secrets behind the perfect seafood recipe that’s not only easy to make but also incredibly rewarding.
In this post, we’ll dive into the details of creating a seafood casserole that can satisfy both your cravings and dietary needs. You’ll find everything from ingredient suggestions to step-by-step instructions, and even tips on making it healthier without losing flavor.
Ingredients List
A key part of any successful seafood casserole recipe is the combination of fresh ingredients that will bring out the natural flavors of the seafood while creating a creamy, savory base. Here’s the list of ingredients you’ll need:
Main Ingredients:
- Seafood mix (shrimp, scallops, crab, and white fish) – 2 cups (fresh or frozen)
- Cream of mushroom soup – 1 can (you can substitute with a low-fat version)
- Mayonnaise – 1/2 cup
- Cheddar cheese – 1 cup, shredded (use a low-fat cheese for a healthier option)
- Breadcrumbs – 1/2 cup (consider whole-grain breadcrumbs for a healthier twist)
- Lemon juice – 1 tablespoon (freshly squeezed for best flavor)
- Fresh parsley – 2 tablespoons, chopped (adds color and freshness)
- Butter – 1 tablespoon (you can substitute with olive oil for a heart-healthy option)
- Garlic – 2 cloves, minced (for aromatic depth)
Optional Additions:
- Green peas – 1/2 cup (for a pop of color and added nutrients)
- Mushrooms – 1/2 cup, sliced (for an extra savory layer)
- Red bell peppers – 1, diced (adds sweetness and a splash of color)
- Paprika – 1/2 teaspoon (for a touch of heat and color)
Feel free to adjust the seafood mix based on what you have available or your personal preferences. Fresh seafood will provide the most flavor, but frozen options work great too, especially when you’re looking for convenience.
Timing
This seafood casserole recipe is a quick and easy dish to prepare, making it a perfect option for a weeknight dinner or a weekend get-together.
- Preparation time: 15 minutes
- Cooking time: 35 minutes
- Total time: 50 minutes
In comparison to traditional casseroles that can take over an hour to prepare and bake, this seafood casserole recipe is significantly quicker, saving you 20% of the time while delivering the same level of satisfaction.

Step-by-Step Instructions
Now that you have all the ingredients ready, let’s walk through the process of making this delicious seafood casserole. Each step has been broken down into easy-to-follow actions, with tips to ensure your casserole turns out perfect every time.
Step 1: Preheat the Oven
Start by preheating your oven to 350°F (175°C). This ensures that your casserole will bake evenly and be ready in the specified time. Make sure to grease your baking dish lightly with butter or cooking spray to prevent sticking.
Step 2: Prepare the Seafood
If you’re using frozen seafood, make sure it is completely thawed and drained to avoid excess water in your casserole. Chop your seafood into bite-sized pieces for easier eating and a more even texture throughout the dish.
Step 3: Make the Creamy Base
In a mixing bowl, combine the cream of mushroom soup, mayonnaise, lemon juice, and minced garlic. Stir these ingredients together until smooth. This mixture will form the creamy base of your casserole. You can add in any optional ingredients here, like green peas or mushrooms, to enhance the flavor and texture.
Step 4: Combine Seafood and Cheese
Add the chopped seafood to the creamy base, followed by the shredded cheddar cheese. Stir everything gently to ensure that the seafood is well-coated in the sauce. Be sure to not overmix, as you don’t want to break up the seafood too much.
Step 5: Assemble the Casserole
Transfer the seafood and creamy mixture into the prepared baking dish. Spread it out evenly and smooth the top with a spatula. Sprinkle the breadcrumbs evenly on top of the casserole to create a crunchy, golden-brown topping. If desired, sprinkle some paprika on top for color and a slight kick.
Step 6: Bake
Place the casserole in the oven and bake for 30-35 minutes, or until the top is golden and the casserole is bubbly. You can check the doneness by inserting a fork into the middle—if it comes out hot and clean, the casserole is ready.
Step 7: Garnish and Serve
Once baked, remove the casserole from the oven and let it sit for a few minutes to set. Garnish with fresh parsley before serving for an added touch of color and flavor.

Nutritional Information
Here’s a breakdown of the nutritional information for a standard serving of this seafood casserole recipe. The values are approximate and can vary depending on your choice of ingredients:
- Calories: 320 per serving
- Protein: 23g
- Fat: 21g (with healthy fats from seafood and mayonnaise)
- Carbohydrates: 18g
- Fiber: 2g
- Sodium: 550mg
- Cholesterol: 120mg
- Vitamin C: 25% of the daily value (due to lemon juice and parsley)
- Calcium: 15% of the daily value (from the cheese)
Healthier Alternatives for the Recipe
For those looking to make a healthier version of this seafood casserole, here are some options:
- Use low-fat or fat-free mayonnaise to reduce calories.
- Switch to a plant-based cream of mushroom soup for a dairy-free option.
- Opt for whole-grain breadcrumbs to add fiber and nutrients.
- Replace the butter with olive oil for heart-healthy fats.
- Include more vegetables like spinach or zucchini to increase the dish’s nutritional value without compromising flavor.
With these simple substitutions, you can tailor the recipe to various dietary preferences and health goals.
Serving Suggestions
A seafood casserole is versatile and can be paired with many different side dishes. Here are a few serving suggestions to make your meal more complete:
- Serve with a light salad: A crisp, green salad with a tangy vinaigrette will balance the richness of the casserole.
- Pair with roasted vegetables: Roasted broccoli, asparagus, or Brussels sprouts provide a delicious, nutrient-packed side.
- Serve with garlic bread: For a more indulgent option, serve your casserole with freshly baked garlic bread to soak up the creamy sauce.
These sides will complement the seafood casserole beautifully and turn your meal into a satisfying feast.
Common Mistakes to Avoid
While making a seafood casserole recipe is relatively simple, there are a few common mistakes that can affect the outcome:
- Overcooking the seafood: Seafood cooks quickly, so avoid overcooking it to prevent it from becoming rubbery.
- Using canned soup with too much sodium: Opt for a low-sodium version of the cream of mushroom soup to keep your dish healthier.
- Not draining frozen seafood thoroughly: Any excess water can make the casserole too runny. Ensure your seafood is well-drained.
- Skipping the resting time: Allow the casserole to sit for a few minutes before serving to allow the flavors to meld and the casserole to set.

By avoiding these pitfalls, you’ll ensure a perfect casserole every time!
Storing Tips for the Recipe
If you happen to have leftovers or want to prep ahead, storing your seafood casserole is easy:
- Refrigerating: Store leftover casserole in an airtight container in the fridge for up to 2-3 days.
- Freezing: For longer storage, you can freeze the casserole before baking. Wrap it tightly with plastic wrap and aluminum foil and store it for up to 3 months. When ready to bake, thaw it overnight in the fridge and bake as usual.
- Reheating: To reheat, place the casserole in a preheated oven at 350°F (175°C) for about 15-20 minutes, or until heated through.
Conclusion
In just under an hour, you can create a delicious and satisfying seafood casserole recipe that’s both comforting and nutritious. This dish is perfect for any occasion, whether you’re cooking for a family meal or hosting friends for dinner. With simple ingredients, easy instructions, and the ability to customize for various dietary needs, this recipe is a winner.
Don’t forget to try the recipe and share your thoughts in the comments below! If you enjoyed this post, subscribe for more delicious recipes and cooking tips.
FAQs
Can I use frozen seafood for this recipe?
Yes, you can use frozen seafood. Just ensure it’s thawed and well-drained before using it in the casserole.
Can I make this dish dairy-free?
Yes, simply substitute the mayonnaise and cheese with dairy-free alternatives like vegan mayo and plant-based cheese.
How do I know when the casserole is done baking?
The casserole is done when the top is golden brown and the casserole is bubbling. You can also insert a fork in the center to check if it’s hot all the way through.
Can I make the casserole ahead of time?
Yes, you can prepare the casserole in advance and refrigerate it until ready to bake. Just increase the baking time slightly if it’s cold from the fridge.
What should I serve with this casserole?
Try serving it with a fresh green salad, roasted vegetables, or garlic bread for a complete meal.
Print
Seafood Casserole Recipe
- Total Time: 50 minutes
- Yield: 4 servings
Description
A rich and creamy seafood casserole that combines a variety of seafood, including shrimp, scallops, and crab, with a cheesy, savory sauce and a crispy breadcrumb topping. Perfect for family dinners, special occasions, or a comforting weeknight meal.
Ingredients
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Seafood mix (shrimp, scallops, crab, and white fish) – 2 cups (fresh or frozen)
-
Cream of mushroom soup – 1 can (low-fat version can be used)
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Mayonnaise – 1/2 cup
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Cheddar cheese – 1 cup, shredded (low-fat option can be used)
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Breadcrumbs – 1/2 cup (whole-grain breadcrumbs for a healthier twist)
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Lemon juice – 1 tablespoon (freshly squeezed)
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Fresh parsley – 2 tablespoons, chopped
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Butter – 1 tablespoon (can be substituted with olive oil for a heart-healthy version)
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Garlic – 2 cloves, minced
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Green peas – 1/2 cup (optional)
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Mushrooms – 1/2 cup, sliced (optional)
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Red bell peppers – 1, diced (optional)
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Paprika – 1/2 teaspoon (optional)
Instructions
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Preheat the oven to 350°F (175°C) and grease your baking dish with butter or cooking spray.
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Prepare the seafood: If using frozen seafood, ensure it’s thawed and well-drained. Chop into bite-sized pieces.
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Prepare the creamy sauce: In a mixing bowl, combine the cream of mushroom soup, mayonnaise, lemon juice, and minced garlic. Stir until smooth. Add any optional ingredients like green peas or mushrooms for added flavor and texture.
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Add seafood and cheese: Gently fold the chopped seafood and shredded cheddar cheese into the creamy mixture.
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Assemble the casserole: Transfer the mixture into the prepared baking dish, smoothing the top with a spatula. Sprinkle the breadcrumbs evenly on top.
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Bake: Place the casserole in the oven and bake for 30-35 minutes or until the top is golden and the casserole is bubbling.
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Garnish: Once baked, remove the casserole from the oven and let it cool for a few minutes before garnishing with fresh parsley.
Notes
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You can use a variety of seafood based on personal preference, including lobster or fish fillets.
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If you prefer a spicier casserole, consider adding a pinch of cayenne pepper or chili flakes.
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For a dairy-free version, use plant-based mayonnaise and vegan cheese.
- Prep Time: 15 minutes
- Cook Time: 35 minutes
- Category: Main Course
- Method: Baking
- Cuisine: American
Keywords: Seafood casserole, seafood recipe, easy seafood casserole, creamy seafood casserole, casserole recipes, seafood dinner